Ronald P. Caputo, MD, FACC, FSCAI

EDUCATION

  • 1984 B.S. in Biology, Georgetown University, Washington DC

    1988 MD, Georgetown University Medical School, Washington DC


POSTDOCTORAL TRAINING

  • 1988 - 1989 Intern in Medicine, University of Massachusetts Medical Center, Worcester MA.

  • 1989 - 1990 Junior Medical Resident, University of Massachusetts Medical Center, Worcester MA.

  • 1990 - 1991 Senior Medical Resident, University of Massachusetts Medical Center, Worcester MA.

  • 1991 - 1992 Chief Medical Resident, University of Massachusetts Medical Center, Worcester MA.

  • 1992 - 1996 Research and Clinical Fellow in Medicine (Cardiology), Harvard Medical School and the Beth Israel Hospital, Boston MA.

LICENSURE AND CERTIFICATION

  • 1990 - Massachusetts State License for Medicine and Surgery

  • 1991 - Diplomate - American Board of Internal Medicine

  • 1995 - Diplomate - American Board of Internal Medicine, Cardiovascular Disease

  • 1996 - New York State License for Medicine and Surgery

EMPLOYMENT

1996 - Invasive/Interventional Cardiologist, S.J.H. Cardiac Catheterization Associates, P.C., Syracuse, NY.

ACADEMIC APPOINTMENTS

1991 - 1992 Instructor in Medicine, University of Massachusetts Medical School, Worcester MA.
1995 - 1996 Instructor in Medicine, Harvard Medical School, Boston MA.
1998 - Assistant Clinical Professor of Medicine, State University of New York Health Science Center.


HOSPITAL/CLINICAL APPOINTMENTS

  • 1989 - 1992 Primary Care Physician, Evening Medical Clinic, Tri - River Family Health Center, Uxbridge MA.

  • 1990 - 1992 Attending Physician, Emergency Room, Worcester Hahneman Hospital, Worcester MA.

  • 1991 - 1992 Urgent Care Attending Physician, Urgent Care Center, Holden Hospital, Holden MA.

  • 1992 - 1993 In House Physician, Special Care Unit, Marlborough Hospital, Marlborough MA.

  • 1992 - 1996 Clinical Fellow, Beth Israel Hospital, Boston MA.

  • 1993 - 1994 In House Physician, Intensive Care Unit, Winthrop Hospital, Winthrop MA.

  • 1994 - 1996 In House Physician, Melrose - Wakefield Hospital, Melrose MA.

  • 1996 - Attending Invasive Cardiologist, Cardio Lab, St. Joseph's Hospital, Syracuse, N.Y.

  • 1996 - Attending Invasive Cardiologist, Cardiac Catheterization Laboratory, Crouse Medical Center, Syracuse, N.Y.

MAJOR COMMITTEE ASSIGNMENTS

  • 1988 - 1992 Executive Residency Committee, University of Massachusetts Medical Center, Worcester MA.

  • 1991 - 1992 Resident Selection Committee, University of Massachusetts Medical Center, Worcester MA.

  • 1991 - 1992 Pharmacy Committee, University of Massachusetts Medical Center, Worcester MA.

  • 1991 - 1992 Medical Quality Assurance Committee, University of Massachusetts Medical Center, Worcester MA.

  • 1991 - 1992 Housestaff Implementation Committee, Milford Hospital, Milford MA.

  • 1991 - 1992 Co - Chairman, Medical Journal Club Committee, University of Massachusetts Medical Center, Worcester MA.

  • 1996 - Cardiothoracic Surgery Committee, St. Joseph's Hospital, Syracuse N.Y.

  • 1999 - Investigational Review Board, St. Joseph's Hospital, Syracuse NY.

  • 1999 - Representative to the Cardiovascular Advisory Committee, Medical Society of the State of New York

  • 1999 - Editorial Consultant, Catheterization and Cardiovascular Interventions (Journal of the Society for Cardiac Angiography and Interventions)

  • 2000 - Catheterization Laboratory Committee, Crouse Hospital, Syracuse N.Y.

ORGANIZATIONS AND SOCIETIES

  • 1988 - 1998 Massachusetts Medical Society

  • 1988 - 1992 Worcester District Medical Society

  • 1991 - Member, American College of Physicians.

  • 1992 - 1996 Norfolk County Medical Society

  • 1993 - Member, American Heart Association

  • 1996 - Member, Medical Society of the State of New York

  • 1996 - Member, Onondaga County Medical Society

  • 1997 - Member, Society for Coronary Angiography and Intervention

  • 1997 - Fellow, American College of Cardiology

  • 2000 - Fellow, Society for Cardiac Angiography and Interventions

MAJOR ADMINISTRATIVE RESPONSIBILITIES

  • 1993 Co - Director, Core Angiographic Laboratory, Thrombolysis in Myocardial Infarction (TIMI) - 9 Study, Beth Israel Hospital, Boston, MA.

  • 1993 Co - Investigator, Thrombolysis in Myocardial Infarction (TIMI) - 8 Study, Beth Israel Hospital, Boston, MA.

  • 1996 Co - Director Interventional Cardiology Research, St. Joseph's Hospital, Syracuse, N.Y.

  • 1997 Principle Investigator, EXTRA Study, St. Joseph's Hospital, Syracuse, N.Y.

  • 1998 Principle Investigator, Beta - Cath Study, Crouse Hospital, Syracuse, N.Y.

  • 1999 Principle Investigator, START study, Crouse Hospital, Syracuse, N.Y.

  • 2000 Principle Investigator, PREDICT Study, St. Joseph's Hospital, Syracuse, N.Y.

  • 1999 Principle Investigator, SAFER Study, St. Joseph's Hospital, Syracuse, N.Y.

  • 2000 Principle Investigator, RAPIER Study, St. Joseph's Hospital, Syracuse, N.Y.

  • 2001 Principle Investigator, SWING Study, St. Joseph's Hospital, Syracuse N.Y.

  • 2001 Principle Investigator, SPLASH Study, St. Joseph's Hospital, Syracuse N.Y.

  • 2001 Principle Investigator, SIRIUS Study, St. Joseph's Hospital, Syracuse N.Y.

  • 2001 Principle Investigator, FIRE Filterwire Study, St. Joseph's Hospital, Syracuse N.Y.

BUSINESS INTERESTS

  • 1999 - Chairman, Head of Scientific Development and founding partner of AngioLink Co. This private company, based in Stoughton MA, is dedicated to assisting physicians in new product development, specifically; refining concepts, engineering and design, patent and legal support, prototype development, pre-clinical and clinical testing, marketing and sales. Mainly focused in the fields of interventional cardiology, peripheral vascular intervention and cardiothoracic surgery.

  • 2001 - Medical Advisory Board, Boston Scientific Company, Natick MA.


MAJOR RESEARCH INTERESTS

1. Utilization of intracoronary ultrasound for optimal percutaneous coronary revascularization in humans (includes participation in the OARS and RAVES multicenter studies).

2. Multicenter studies utilizing new techniques for percutaneous coronary revascularization (TIMI - 3, TIMI - 4, TIMI - 8, TIMI - 9, STRESS, OARS, RAVES, STRATUS, DART, VEGAS, NIRVANA, EXTRA, CADILLAC, SPORT, Beta Cath, START, PREDICT, SAFER, RAPIER, Filterwire).

3. Feasibility and efficacy of primary PTCA for the treatment of acute myocardial infarction (Author, Primary Angioplasty section of Cardiology- Up to Date, Stent PAMI and CADILLAC trials, created primary PTCA quality assurance program at St. Joseph's Hospital, Syracuse N.Y.).

4. Clinical trials investigating new stent designs (EXTRA, NIRVANA, NIRON, PREDICT, SIRIUS, VISION).

5. Transradial Catheterization - applicability to patient subsets, clinical outcomes etc.

6. Development of hemostasis devices applied to percutaneous vascular access.

PUBLICATIONS

Original Reports

1. Caputo RP, Carrao J, Lew R, Becker RC. Effect of serum cholesterol on hemorrhagic complications following thrombolytic therapy for acute myocardial infarction. Cardiology 1991;79:211-218.

2. Becker RC, Caputo RP, Ball S, Corrao JM, Baker S, Gore JM. Hemorrhagic potential
of combined diltiazem and recombinant tissue-type plasminogen activator administration. Am Heart J 1993;126:11-14.

3. Caputo RP, Cohen DJ, Baim DS, Kuntz RE. Extravasation of Thrombus into the
aortic root: A complication following the use of an infusion catheter for intra-graft thrombolysis. Catheterization and Cardiovascular Diagnosis. 1995

4. Caputo RP, Chafizedeh E, Stoler R, Lopez J, Cohen DJ, Kuntz RE, Carrozza JP,
Baim DS. Stent Jail: A minimum security prison. Am J Cardiol 1996;77:1226-1230.

5. Sukin C, Baim DS, Caputo RP, Ho KKL, Laham R, Flatley M, Carrozza JP, Cohen DJ. The impact of optimal stenting techniques on cardiac catheterization laboratory resource utilization and costs. Am J Cardiol 1997;79:275-280.

6. Lopez JJ, Ho KKL, Stoler R, Caputo RP, Carrozza JP, Kuntz RE, Baim DS, Cohen DJ. Percutaneous treatment of protected and unprotected left main coronary stenoses with new devices: Immediate angiographic results and intermediate-term follow up. J Am Coll Cardiol 1997;29:345-352.

7. Caputo RP, Ho KKL, Stoler R, Sukin C, Lopez JJ, Cohen DJ, Kuntz RE, Berman A, Carrozza JP, Baim DS. Effect of continuous quality improvement analysis on the delivery of primary percutaneous transluminal coronary angioplasty for acute myocardial infarction. Am J Cardiol 1997;79:1159-1164.

8. Lopez JJ, Edelman ER, Stamler A, Hibberd MG, Pottumarthi P, Caputo RP,
Carrozza, JP, Douglas PS, Sellke FW, Simons M. Basic fibroblast growth factor in a porcine model of chronic myocardial ischemia: A comparison of angiographic, echocardiographic and coronary flow parameters. J Pharm and Exp Therapeutics 1997;282:385-390.

9. Sukin CA, Baim DS, Caputo RP, Ho KKL, Laham RJ, Flately MG, Carrozza JP, Cohen DJ. The impact of optimal stenting techniques on cardiac catheterization laboratory resource utilization and costs. Am J Cardiol 1997;79:275-280.

10. Caputo RP, Rosenberg J, Fedele K, Giambartolomei A. Myocardial ischemia resulting from spontaneous dissection in a patient with massive bilateral sinus of valsalva aneurysms. Cathet and Cardiovasc Diagn 1999;47:194-198.

11. Simons AJ, Caputo RP, Esente P, Giambartolomei A, Bowser M, Reger M, Walford G. An unusual complication during deployment of a Multi-Link stent. Cathet and Cardiovasc Diagn 1999;47:58-60.

12. Caputo RP, Simons A, Giambartolomei A, Grant W, Fedele K, Esente P. Transradial cardiac catheterization in patients with prior brachial artery cutdown. Cathet and Cardiovasc Diagn 1999;48:271-274.

13. Caputo RP, Amin N, Marvasti M, Wagner S, Levy C, Giambartolomei A. Percutaneous treatment of a saphenous vein graft perforation with and autologous vein covered stent. Cathet and Cardiovasc Diagn 1999;48:382-386.

14. Caputo RP, Abraham S, Churchill D. Transradial coronary stent placement in a patient with severe idiopathic autoimmune thrombocytopenic purpura. J Invas Cardiol 2000; 12:365-368.

15. Caputo RP, Simons A, Giambartolomei A, Grant W, Fedele K, Abraham S, Reger MJ, Walford GD, Esente P. Transradial cardiac catheterization in elderly patients. Cathet and Cardiovasc Intervent 2000; 51:287-290.

16. Caputo RP, Simons AJ, Giambartolomei A, Grant W, Fedele K, Abraham S, Felice P, Reger MJ, Walford GD, Esente P. Safety and Efficacy of Repeat Transradial Access for Cardiac Catheterization Procedures. Cathet Cardiovasc Intervent 2001;54:188-190.

17. Caputo RP, Giambartolomei A, Simons AJ, Reger MJ, Wagner S, Esente P.
Use of Combination Glycoprotein IIb/IIIa inhibitor and Direct Thrombin Inhibitor Drugs to Support Percutaneous Coronary Stent placement in a Patient with Renal Insufficiency and Heparin Induced Thrombocytopenia. J Invas Cardiol 2001;13:657-659.

18. Baim DS, Flately M, Caputo RP, O'Shaughnessy C, Low R, Fanelli C, Popma J, Fitzgerald P, Kuntz R. Comparison of Predilatation vs. Direct Stenting in Coronary Treatment using the Medtronic AVE S670 Coronary Stent System (The Predict Trial). Am J Cardiol. 2002; 88: 1364-1369.

19. Cutlip DE, MD, Ricciardi, MJ MD, Carrozza JP, MD, Giri S, MD, Dua V, MD, Garringer J, MD, Ling FS, MD, Caputo RP, MD. A Randomized Comparison of Standard Primary Angioplasty To Facilitated Primary Angioplasty with Early Tirofiban Administration in the Emergency Room. Am Heart J. 2001 (in press)


Abstracts

1. Caputo RP, Corrao J, Lew R, Becker RC. The effect of serum cholesterol on hemorrhagic complications following rt-PA administration. Blood 1990;76:1649a.

2. Caputo RP, Becker RC. Environmental tobacco smoke as a risk factor for coronary heart disease: Assessment of health beliefs and practices in medical students and resident physicians. Third Annual American Heart Association Massachusetts Affiliate Cholesterol Conference, February 1992.

3. Becker RC, Caputo RP, Ball S, Corrao J, Ansell J, Baker S, Gore J. Hemorrhagic potential of combined intravenous diltiazem and tissue plasminiogen activator administration. J Am Coll Cardiol 1993;21(2):397A.

4. Paik GY, Caputo RP, Nunez BD, Baim DS, Carrozza JP. Thrombus contains soluble factors which decrease blood flow in swine coronary arteries through a nitric oxide-dependent pathway. J Am Coll Cardiol 1994;23:64A.

5. Wood MJ, Cohen DJ, Laham RJ, Caputo RP, Carrozza JP, Lopez JJ, Baim DS. Catheter based revascularization in patients with prior coronary bypass surgery - increasing prevalence and new device use in 1993 compared to 1988. Circulation 1994;90(4):I63.

6. Caputo RP, Kuntz RE, Baim DS, Carrozza JP. Balloon counterpulsation in the ascending aorta provides greater coronary blood flow compared with descending counterpulsation. Circulation 1994;90(4):I604.

7. Caputo RP, Lopez JJ, Ho KKL, Paik GY, Kuntz RE, Baim DS, Carrozza JP. Intravascular ultrasound analysis of routine high pressure balloon post-dilatation after Palmaz-Schatz stent deployment. J Am Coll Cardiol 1995;49A.

8. Caputo RP, Ho KKL, Lopez JJ, Stoler RC, Cohen DJ, Carrozza JP. Quantitative angiographic comparison of Palmaz-Schatz stent implantation with and without intravascular ultrasound. Circulation 1995;92(8):I545.

9. Sukin CA, Caputo RP, Laham RJ, Carrozza JP, Cohen DJ. Catheterization laboratory
resource utilization and costs for Palmaz-Schatz native coronary artery stenting in 1995 vs STRESS. Circulation 1995;92(8):I661.

10. Lopez JJ, Starebier A, Edelman ER, Hibberd MG, Caputo RP, Carrozza JP, Prasad PV, Douglas PS, Sellke FW, Simons M. Local bFGF treatment results in angiographic collateral development, dose related increase in coronary flow and myocardial function in chronic myocardial ischemia. Circulation 1995;92(8):I67.

11. Lopez JJ, Caputo RP, Ho KKL, Stoler R, Carrozza JP, Kuntz RE, Baim DS, Cohen DJ. Percutaneous treatment of left main coronary stenoses with new devices: Acute results and intermediate term follow-up. Circulation 1995;92(8):I147.

12. Carrozza JP, Kereiakas D, Caputo RP, Knopf WD, Nolan K, Chase K, Chen X,
Senerchia C, Rodriguez O, Cutlip D.P. Final acute, 30-day, and 6-month clinical and angiographic outcome from the multicenter, randomized EXTRA trial comparing the operator-mounted XT and Palmaz-Schatz coronary stents. Circulation 1998;17:I661.

13. Caputo RP, Giambartolomei A, Simons A, Esente P, Keriakes D, Ho KKL, Carrozza JP. Small vessel stenting - Comparison of modular vs. slotted tube design. Six month results from the EXTRA Trial. J Am Coll Cardiol 2000;35(2):56A.

14. Shimodozona, Honda Y, Caputo RP, O'Shaughnessy CD, Low RL, Rutherford BD,Zetterlund PC, Rogers, CDK, Yock PG, Baim DS, Fitzgerald PJ. Acute and chronic vessel responses to direct stenting vs. stenting with predilatation: A serial intravascular ultrasound study. J Am Coll Cardiol 2001;37:26A.

15. Caputo RP, A. Ebner, G. Kanner, K. Eliasen, S. Tallarida, T. Piemonte, S. Bollinger Percutaneous Femoral Arteriotomy Repair - Initial Experience with a Novel Staple Closure Device. J Am Coll Cardiol 2001;88(5A):33G.

16. Rinaldi MJ, Piana RN, Caputo RP, Gordon PC, Lopez JJ, Dauerman HL, Hammes LN, Holmes DR, Shaikh SR, Ryan TJ, Warner JJ, Zidar JP, Kiernan FJ, Moussa I, Palacios IF, Cox DA, Lim J, Murphy S, Cutlip DE, Ho KKL, Gibson M, Cohen DJ. Multicenter Study of Stent Thrombosis in the Modern Era. J Am Coll Cardiol 2001;88(5A):4G.


Book Chapters

1. Caputo, RP. Acute Heart Failure. In Irwin RS, Cerra FB, JM Rippe (eds): Intensive Care Medicine 4th Edition, Philadelphia, PA: Lippencott - Raven, 1999, pp 413 - 428.

2. Caputo, RP. Primary Angioplasty. In Podrid P (ed): Cardiology UpToDate, Wellesley MA, 1999.

3. Caputo RP, Grossman W. Brachial Cutdown Approach. In Baim DS, Grossman W (eds): Cardiac Catheterization, Angiography, and Intervention 6th Edition, New York, NY: Williams & Wilkins, 2000, pp101 - 124.

4. Caputo RP, Becker RC. Acute Heart Failure. In Irwin RS, Rippe JM (eds): Munual of Intensive Care Medicine 3rd Edition, New York, N.Y.: Lippincott Williams & Wilkins, 2000, pp171 - 176.


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